Kataoka K, Yamada S, Toki N
Acta Haematol. 1984;71(2):90-6. doi: 10.1159/000206563.
It was confirmed that activation of the kallikrein-kinin enzyme system in cryoglobulinemia might be initiated by activation of factor XII to factor XIIa by cryoglobulin. It was also demonstrated that cryoglobulin or fibrin clots lost their ability to redissolve on warming to 37 degrees C, and consequently the lysis time of fibrin clots was increased.
已证实,冷球蛋白血症中激肽释放酶 - 激肽酶系统的激活可能由冷球蛋白将因子XII激活为因子XIIa引发。还证实,冷球蛋白或纤维蛋白凝块在升温至37摄氏度时失去了重新溶解的能力,因此纤维蛋白凝块的溶解时间增加。