人胰岛的胆碱能神经支配。

The cholinergic innervation of human pancreatic islets.

作者信息

Amenta F, Cavallotti C, de Rossi M, Tonelli F, Vatrella F

出版信息

Acta Histochem. 1983;73(2):273-8. doi: 10.1016/S0065-1281(83)80038-5.

Abstract

The cholinergic innervation of pancreatic islets was investigated in the human using operatory samples. In order to analyze the nature of stained cholinergic nerve fibers some specimens were incubated in a solution containing 6-hydroxydopamine (6-HDA) to obtain a selective degeneration of adrenergic nerves. Cholinergic nerve fibers are present in human pancreatic islets, and appear to be organized in an external peri-insular plexus. Some nerve fibers from the peri-insular plexus enter the islets and seem to innervate directly various types of endocrine insular elements. The 6-HDA treatment does not alter the distribution pattern of cholinergic nerve fibers within pancreatic islets.

摘要

利用手术标本对人体胰岛的胆碱能神经支配进行了研究。为了分析染色的胆碱能神经纤维的性质，一些标本在含有6-羟基多巴胺（6-HDA）的溶液中孵育，以实现肾上腺素能神经的选择性变性。胆碱能神经纤维存在于人类胰岛中，并且似乎在外周胰岛丛中形成结构。一些来自外周胰岛丛的神经纤维进入胰岛，似乎直接支配各种类型的胰岛内分泌细胞。6-HDA处理不会改变胰岛内胆碱能神经纤维的分布模式。