Pasanen V J, Mäkelä O
Scand J Immunol. 1984 Feb;19(2):123-7. doi: 10.1111/j.1365-3083.1984.tb00907.x.
The direct 5-day plaque-forming cell response of different inbred mouse strains to pneumococcal polysaccharide type III (SSS-III) varied from more than 10,000 per spleen, in BALB/c mice, to less than 2000 in C57BL mice. Responses of Igh congenic and recombinant inbred lines bearing different combinations of BALB/c and C57BL genes indicate that two or more gene loci are involved in controlling high or low responses. At least one is in the Igh-V region since BALB/c, BAB-14, and CB-8 KN mice (Igh-Va) had two to four times higher responses than CB-20 and CB-16 KN mice (Igh-Vb). Other gene loci must be involved, but nothing can be said about them at present.
不同近交系小鼠对Ⅲ型肺炎球菌多糖（SSS-III）的直接5天噬斑形成细胞反应有所不同，在BALB/c小鼠中，每个脾脏超过10000个，而在C57BL小鼠中则少于2000个。携带BALB/c和C57BL基因不同组合的Igh同源近交系和重组近交系的反应表明，两个或更多基因座参与控制高反应或低反应。至少有一个在Igh-V区域，因为BALB/c、BAB-14和CB-8 KN小鼠（Igh-Va）的反应比CB-20和CB-16 KN小鼠（Igh-Vb）高两到四倍。其他基因座肯定也参与其中，但目前对此还无法定论。
