Wagle W A, Smith T W, Weiner M
AJNR Am J Neuroradiol. 1984 Mar-Apr;5(2):171-6.
Seven cases of nontraumatic intracerebral hemorrhage due to histologically confirmed cerebral amyloid angiopathy were observed over a period of 2 1/2 years. Initial computed tomographic (CT) scans demonstrated lobar hemorrhages in all but one patient, who had presented with corpus callosum hemorrhage. Superficial location, irregular borders, and surrounding edema were characteristic features. Angiography was performed in three cases. Findings included mass effect (three cases), opercular branch occlusion (one case), and pericallosal irregularity (one case), all in the areas of the hemorrhage. Clinically, none of the patients had a history of prior cerebrovascular disease. Mild hypertension had been present in three patients and dementia in two. These findings suggest that cerebral amyloid angiopathy is not a rare cause of atraumatic lobar hemorrhage, particularly in a normotensive, elderly population.
在2年半的时间里，观察到7例经组织学证实为脑淀粉样血管病所致的非创伤性脑出血。最初的计算机断层扫描（CT）显示，除1例表现为胼胝体出血的患者外，其余所有患者均为脑叶出血。表浅部位、边界不规则及周围水肿是其特征性表现。3例患者进行了血管造影。结果包括占位效应（3例）、岛叶分支闭塞（1例）和胼周不规则（1例），均位于出血区域。临床上，所有患者均无既往脑血管疾病史。3例患者有轻度高血压，2例有痴呆。这些发现表明，脑淀粉样血管病是无创伤性脑叶出血的一个并非罕见的病因，尤其在血压正常的老年人群中。
