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[阿尔茨海默病患者的多灶性脑出血与白质淀粉样血管病]

[Multiple cerebral hemorrhage and amyloid angiopathy of the white matter in a case of Alzheimer's disease].

作者信息

Lucas C, Parent M, Delandsheer E, Delacourte A, Fournier Y, Défossez A, Leys D

机构信息

Service de Neurologie B, Centre Hospitalo-Universitaire de Lille.

出版信息

Rev Neurol (Paris). 1992;148(3):218-20.

PMID:1604138
Abstract

Amyloid angiopathy is a common pathological finding in Alzheimer's disease. It usually involves leptomeningeal and cortical vessels but spares the white matter. It may cause lobar cerebral hemorrhages at a late stage of the disease. We report a case of Alzheimer's disease at an early stage with diffuse lesions of amyloid angiopathy including some within the white matter, apparently responsible for 2 deep and 1 superficial cerebral hemorrhages.

摘要

淀粉样血管病是阿尔茨海默病常见的病理表现。它通常累及软脑膜和皮质血管,但不累及白质。在疾病晚期可能导致脑叶出血。我们报告一例早期阿尔茨海默病病例,其淀粉样血管病呈弥漫性病变,包括白质内的一些病变,显然这些病变导致了2次深部脑出血和1次浅表脑出血。

相似文献

1
[Multiple cerebral hemorrhage and amyloid angiopathy of the white matter in a case of Alzheimer's disease].[阿尔茨海默病患者的多灶性脑出血与白质淀粉样血管病]
Rev Neurol (Paris). 1992;148(3):218-20.
2
Intracerebral hemorrhage secondary to cerebral amyloid angiopathy.脑淀粉样血管病继发脑出血
Radiology. 1984 May;151(2):397-400. doi: 10.1148/radiology.151.2.6709910.
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Cerebrovascular amyloidosis with cerebral hemorrhage.伴有脑出血的脑血管淀粉样变性
J Neurol. 1977 Feb 17;214(3):195-206. doi: 10.1007/BF00316150.
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Cerebral amyloid angiopathy in Down's syndrome.
Clin Neuropathol. 1986 Nov-Dec;5(6):257-60.
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[An Alzheimer's disease case showing recurrent subcortical hemorrhage: an autopsy findings with immunohistochemical studies of cerebral amyloid deposits].
Rinsho Shinkeigaku. 1989 Jul;29(7):936-9.
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[Multiple hemorrhagic cerebral amyloid angiopathy associated with leukoencephalopathy].[与白质脑病相关的多发性出血性脑淀粉样血管病]
No To Shinkei. 1990 Jul;42(7):689-93.
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Amyloid angiopathy and lobar cerebral haemorrhage.淀粉样血管病与脑叶出血。
J Neurol Neurosurg Psychiatry. 1984 Nov;47(11):1203-10. doi: 10.1136/jnnp.47.11.1203.
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Leukoencephalopathy in diffuse hemorrhagic cerebral amyloid angiopathy.弥漫性出血性脑淀粉样血管病中的白质脑病
Ann Neurol. 1985 Jul;18(1):54-9. doi: 10.1002/ana.410180110.
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Post-anoxic delayed encephalopathy with leukoencephalopathy and non-hemorrhagic cerebral amyloid angiopathy.
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Intracerebral hemorrhage caused by cerebral amyloid angiopathy: radiographic-pathologic correlation.脑淀粉样血管病所致脑出血:影像学与病理学相关性
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引用本文的文献

1
Impact of the biological definition of Alzheimer's disease using amyloid, tau and neurodegeneration (ATN): what about the role of vascular changes, inflammation, Lewy body pathology?使用淀粉样蛋白、tau蛋白和神经退行性变(ATN)对阿尔茨海默病进行生物学定义的影响:血管变化、炎症、路易体病理的作用如何?
Transl Neurodegener. 2018 May 31;7:12. doi: 10.1186/s40035-018-0117-9. eCollection 2018.