Basher H A, Fowler D R, Rodgers F G, Seaman A, Woodbine M
Res Vet Sci. 1984 Jan;36(1):76-80.
The pathogenicity of Listeria monocytogenes for newly hatched chickens exposed to natural infection was examined. Organisms entered through the alimentary tract and dissemination followed bacteraemia. Among a number of symptoms recorded were unilateral and bilateral toe paralysis. In addition to gross abnormalities in the following tissues, histological lesions were seen in the liver, spleen, heart and kidneys of all infected chicks but brain lesions were observed only in birds with central nervous system involvement. The organism was recovered from some tissues derived from apparently healthy chicks as well as those with listeriosis. The use of trypsin in the isolation process increased the probability of a positive result from tissues, reduced the storage time needed and had no adverse effect on the rate of organism growth.
研究了单核细胞增生李斯特菌对自然感染的新孵出小鸡的致病性。该菌通过消化道进入机体，并随菌血症扩散。记录的一系列症状包括单侧和双侧脚趾麻痹。除了以下组织出现肉眼可见的异常外，所有感染雏鸡的肝脏、脾脏、心脏和肾脏均出现组织学病变，但仅在有中枢神经系统受累的雏鸡中观察到脑部病变。该菌可从看似健康的雏鸡以及患有李斯特菌病的雏鸡的一些组织中分离出来。在分离过程中使用胰蛋白酶可提高从组织中获得阳性结果的概率，减少所需的储存时间，且对细菌生长速率没有不利影响。
