Landau J F, Chauvaud S, Vincent P, Duval A M, Dubost C, Delamare J
Arch Mal Coeur Vaiss. 1984 Feb;77(2):228-32.
Chronic right ventricular failure was observed in a young female operated at 25 years of age for Fallot's tetralogy despite surgical refixation of the patch closing the ventricular septal defect which had previously worked loose. The signs of right ventricular failure were due to severe tricuspid incompetence, confirmed at catheterisation and selective right ventricular angiography. They were associated with major hypoproteinaemia which was not due to urinary loss nor hepatic dysfunction, but which was attributed to an exudative enteropathy. The correction of the valvular defect by valvuloplasty was followed by rapid correction of the biological abnormality. The authors review the relationship between serum proteins and cardiac disease, discuss those cardiac affections with known associations with exudative enteropathy, and also the possibilities of reversing the biological abnormality after surgical cure of the causal cardiac lesion.
一名25岁接受法洛四联症手术的年轻女性出现了慢性右心室衰竭,尽管之前松动的室间隔缺损补片已通过手术重新固定。右心室衰竭的体征是由于严重的三尖瓣关闭不全,这在导管检查和选择性右心室血管造影中得到证实。这些体征与严重的低蛋白血症有关,低蛋白血症并非由尿流失或肝功能障碍引起,而是归因于渗出性肠病。通过瓣膜成形术纠正瓣膜缺损后,生物学异常迅速得到纠正。作者回顾了血清蛋白与心脏病之间的关系,讨论了已知与渗出性肠病相关的心脏疾病,以及在导致心脏病变的病因通过手术治愈后逆转生物学异常的可能性。