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[骨髓瘤合并弥漫性肌肉肥大患者血清对培养的人肌肉细胞生长的影响]

[The effect of serum from a patient with myeloma and diffuse muscular hypertrophy on the growth of human muscle cells in culture].

作者信息

Delaporte C, Fardeau M

出版信息

C R Acad Sci III. 1984;298(3):49-54.

PMID:6424890
Abstract

On normal human muscle cells, the serum of a patient with myeloma producing IgG free kappa light chains and with muscle hypertrophy accelerated the myoblast fusion and the myotubes formed were abnormally large. This serum did not enhance cell proliferation.

摘要

在正常人类肌肉细胞上，一名产生游离κ轻链IgG且伴有肌肉肥大的骨髓瘤患者的血清加速了成肌细胞融合，形成的肌管异常大。该血清并未增强细胞增殖。

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C R Acad Sci III. 1984;298(3):49-54.
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In vitro myotrophic effect of serum kappa chain immunoglobulins from a patient with kappa light chain myeloma and muscular hypertrophy.κ轻链骨髓瘤伴肌肉肥大患者血清κ链免疫球蛋白的体外促肌营养作用
J Clin Invest. 1986 Oct;78(4):922-7. doi: 10.1172/JCI112681.