Holle J, Freilinger G
Prog Pediatr Surg. 1984;17:123-30.
The authors report their experiences with sphincter reconstructions by free muscle transplant using a denervated muscle with its blood supply intact. The transplanted muscle is fixed to the remaining functioning sphincter musculature. New muscle fibres grow from this muscle into the transplanted muscle, allowing the reconstructed sphincter to contract voluntarily as well as reflexively. The operative technique depends on the existing sphincter defect. Free muscle transplantation is preferred if the external sphincter is still partially existing. Eight patients were examined 2 years after the reconstruction operation and the result was very satisfactory. Solid and semi-solid stool could be controlled by all patients. Large muscle transplantations carried out after the method reported by Thompson (1971) are followed by an increased intramuscular scar formation, as was shown by our experiments. A denervated muscle transposition with its own blood supply is therefore preferable. The change of innervation allows the transplanted muscle to perform its new function. In the treatment of congenital sphincter malformations, a larger muscle, i.e. transposition of the denervated gracilis muscle, should be used. This operation was performed in 7 cases of incontinence following operations for rectal atresia and in 1 case of extensive posttraumatic destruction of the sphincter apparatus. In only 1 case was continence for solid stool achieved. In 6 patients there was a temporary control of fluid stools, but under stress all patients with complex sphincter malformations soiled.
作者报告了他们使用血供完整的去神经肌肉进行游离肌肉移植重建括约肌的经验。移植的肌肉固定于剩余有功能的括约肌组织。新的肌纤维从该肌肉长入移植肌肉,使重建的括约肌既能自主收缩也能反射性收缩。手术技术取决于现有的括约肌缺损情况。如果外括约肌仍部分存在,优先选择游离肌肉移植。8例患者在重建手术后2年接受检查,结果非常令人满意。所有患者都能控制固体和半固体粪便。如我们的实验所示,按照汤普森(1971年)报告的方法进行大肌肉移植后,肌内瘢痕形成会增加。因此,带有自身血供的去神经肌肉转位更为可取。神经支配的改变使移植肌肉能够发挥其新功能。在治疗先天性括约肌畸形时,应使用更大的肌肉,即去神经股薄肌转位。该手术用于7例直肠闭锁手术后失禁患者和1例括约肌装置广泛创伤后破坏患者。仅1例患者实现了固体粪便的节制。6例患者对液体粪便有临时控制,但在压力下,所有复杂括约肌畸形患者都会弄脏衣物。