Prolactin and gonadotrophin changes following partial seizures in epileptic patients with and without psychopathology.

Postictal serum prolactin, follicle-stimulating hormone, and luteinizing hormone were assessed in 22 epileptic patients with partial seizures. On the basis of their past history they were divided into those with (Group A) and those without (Group B) psychopathology. The results show more significant changes from baseline in Group B. These data suggest that psychopathology may be associated with partial seizures in those patients where spread of seizure activity through limbic system to the diencephalon preferentially occurs.