全身性和部分性癫痫发作后的催乳素和促性腺激素变化
Prolactin and gonadotrophin changes following generalised and partial seizures.
作者信息
Dana-Haeri J, Trimble M r, Oxley J
出版信息
J Neurol Neurosurg Psychiatry. 1983 Apr;46(4):331-5. doi: 10.1136/jnnp.46.4.331.
Abstract
Postictal values of prolactin, LH and FSH have been recorded in patients with both generalised tonic-clonic and partial seizures. Elevations of prolactin and LH were seen immediately and at 20 minutes in males and females with generalised attacks. At sixty minutes values for prolactin had fallen to baseline levels, but LH remained elevated. FSH values were increased in females only, at twenty and sixty minutes. Following partial seizures prolactin was elevated, especially with complex partial seizures, at twenty minutes. These results are discussed in the light of known electrophysiological mechanisms relating to partial seizures, and clinical guidelines for the use of neurohormonal tests in the evaluation of seizures are suggested.
摘要
已记录了全身性强直阵挛发作和部分性发作患者发作后的催乳素、促黄体生成素（LH）和促卵泡生成素（FSH）值。全身性发作的男性和女性在发作即刻及20分钟时催乳素和LH升高。60分钟时催乳素值降至基线水平，但LH仍升高。仅女性在20分钟和60分钟时FSH值升高。部分性发作后，尤其是复杂部分性发作，催乳素在20分钟时升高。根据与部分性发作相关的已知电生理机制对这些结果进行了讨论，并提出了在癫痫评估中使用神经激素检测的临床指南。
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