Gethmann R C
Genetics. 1984 May;107(1):65-77. doi: 10.1093/genetics/107.1.65.
mei- G87 is a recessive meiotic mutant that increases second chromosome nondisjunction in both males and females. A significant proportion of the diplo -2 exceptions are equational . In females, diplo -2 reductional exceptions are usually noncrossovers , but, in equational exceptions, crossover frequency and distribution are the same as that found in the haplo-2 controls. The frequencies of nondisjunction are relatively low: 0.6% in females and 1.3% in males. Nondisjunction frequency is affected by environmental conditions (possibly humidity). The defect in mei- G87 , as in other "second division" mutants, appears to be a failure to maintain sister-chromatid cohesion. mei- G87 increases nondisjunction of only the second chromosome. This may indicate either a weak mutant with only the second chromosome being sensitive enough to misbehave or it may indicate that chromosome-specific regions responsible for sister-chromatid cohesion exist.
mei - G87是一种隐性减数分裂突变体，它会增加雄性和雌性中第二条染色体的不分离现象。相当一部分双二倍体例外情况是均等分离的。在雌性中，双二倍体减数分裂分离例外情况通常是非交换型的，但是，在均等分离例外情况中，交换频率和分布与单倍体 - 2对照中的情况相同。不分离频率相对较低：雌性为0.6%，雄性为1.3%。不分离频率受环境条件（可能是湿度）影响。与其他“第二次分裂”突变体一样，mei - G87的缺陷似乎是未能维持姐妹染色单体的黏连。mei - G87仅增加第二条染色体的不分离现象。这可能表明该突变体较弱，只有第二条染色体足够敏感而行为异常，或者可能表明存在负责姐妹染色单体黏连的染色体特异性区域。
