一种在黑腹果蝇中分配性分离存在缺陷的减数分裂突变体。
A meiotic mutant defective in distributive disjunction in Drosophila melanogaster.
作者信息
Carpenter A T
出版信息
Genetics. 1973 Mar;73(3):393-428. doi: 10.1093/genetics/73.3.393.
Abstract
The female meiotic mutant no distributive disjunction (symbol: nod) reduces the probability that a nonexchange chromosome will disjoin from either a nonexchange homolog or a nonhomolog; the mutant does not affect exchange or the disjunction of bivalents that have undergone exchange. Disjunction of nonexchange homologs was examined for all chromosome pairs; nonhomologous disjunction of the X chromosomes from the Y chromosome in XXY females, of compound chromosomes in females bearing attached-third chromosomes with and without a Y chromosome, and of the second chromosomes from the third chromosomes were also examined. The results suggest that the defect in nod is in the distributive pairing process. The frequencies and patterns of disjunction from a trivalent in nod females suggest that the distributive pairing process involves three separate events-pairing, orientation, and disjunction. The mutant nod appears to affect disjunction only.
摘要
雌性减数分裂突变体“无分布式分离”（符号：nod）降低了非交换染色体与非交换同源染色体或非同源染色体分离的概率；该突变体不影响交换或已发生交换的二价体的分离。对所有染色体对的非交换同源染色体的分离进行了检测；还检测了XXY雌性中X染色体与Y染色体的非同源分离、携带或不携带Y染色体的附着第三染色体雌性中的复合染色体的非同源分离以及第三染色体与第二染色体的非同源分离。结果表明，nod的缺陷在于分布式配对过程。nod雌性中三价体分离的频率和模式表明，分布式配对过程涉及三个独立事件——配对、定向和分离。突变体nod似乎仅影响分离。
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