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与癫痫类型和癫痫发作相关的精神病发生风险。

Risks of occurrence of psychoses in relation to the types of epilepsies and epileptic seizures.

作者信息

Sengoku A, Yagi K, Seino M, Wada T

出版信息

Folia Psychiatr Neurol Jpn. 1983;37(3):221-5. doi: 10.1111/j.1440-1819.1983.tb00322.x.

Abstract

The possible existence of the risks of occurrence of psychoses was examined in relation to the types of epilepsies and epileptic seizures. This study consisted of two investigations: 1) A study of 879 epileptic patients was conducted in which the incidence of psychoses in the different types of epilepsies was surveyed; the result was that the incidence in temporal lobe epilepsy was the highest, being relatively higher than that of other (non-temporal lobe) partial epilepsies but not significantly different from that of generalized epilepsies. 2) A comparative study was carried out on 96 patients with temporal lobe epilepsy in which 48 were psychotic and another 48 were non-psychotic which served as a control group. The differences of seizure symptomatology between the two groups were compared. The results were that the psychotic group was found to exhibit at a significantly higher rate generalized tonic-clonic convulsion and compound seizure manifestations in comparison with the non-psychotic group. The results appear to support the fact that generalizing mechanisms of temporal lobe epileptic manifestations are closely related to a physiopathogenic factor influencing psychoses.

摘要

针对癫痫类型和癫痫发作情况,研究了出现精神病风险的可能性。本研究包括两项调查:1)对879名癫痫患者进行了研究,调查不同类型癫痫中精神病的发病率;结果是颞叶癫痫的发病率最高,相对高于其他(非颞叶)部分性癫痫,但与全身性癫痫的发病率无显著差异。2)对96名颞叶癫痫患者进行了一项对照研究,其中48名患有精神病,另外48名无精神病作为对照组。比较了两组发作症状学的差异。结果发现,与非精神病组相比,精神病组出现全身性强直阵挛性惊厥和复合发作表现的比例明显更高。这些结果似乎支持了这样一个事实,即颞叶癫痫表现的泛化机制与影响精神病的生理致病因素密切相关。

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