Sengupta R P, Stunden R J
Br Med J. 1977 Jan 15;1(6054):142-3. doi: 10.1136/bmj.1.6054.142.
Thirty-nine patients with trigeminal neuralgia, not controlled by medical treatment, were treated by radio-frequency thermocoagulation of the Gasserian ganglion and its posterior rootlets. Thirty-six received satisfactory pain relief. In 30 patients touch sensation in the treated territory was preserved. The corneal reflex was affected in only six patients, two of whom subsequently developed keratitis. There were no other complications apart from a minor unpleasant sensation in eight patients. By selectively destroying pain fibres this technique offers the scope of preserving touch sensation in the treated area. Moreover, the zone of analgesia can be restricted to the affected region by sensory mapping through electrode stimulation before thermocoagulation. Its simplicity, low morbidity, associated short hospital stay, and the increased ability to preserve touch sensation, especially of the cornea, seem to make it preferable to other forms of surgical management for trigeminal neuralgia.
39例药物治疗无法控制的三叉神经痛患者接受了半月神经节及其后根的射频热凝治疗。36例患者疼痛得到满意缓解。30例患者治疗区域的触觉得以保留。仅6例患者角膜反射受到影响,其中2例随后发生角膜炎。除8例患者有轻微不适感觉外,无其他并发症。通过选择性破坏痛觉纤维,该技术能够在治疗区域保留触觉。此外,在热凝之前通过电极刺激进行感觉定位,可将镇痛区域限制在受影响的区域。其操作简单、发病率低、住院时间短,且保留触觉尤其是角膜触觉的能力增强,这似乎使其比其他治疗三叉神经痛的手术方式更具优势。