巨大芽孢杆菌中铁载体对铜毒性的增强作用。
Enhancement of copper toxicity by siderophores in Bacillus megaterium.
作者信息
Arceneaux J E, Boutwell M E, Byers B R
出版信息
Antimicrob Agents Chemother. 1984 May;25(5):650-2. doi: 10.1128/AAC.25.5.650.
Abstract
Chelation of copper by siderophores enhanced the toxicity of copper for Bacillus megaterium. Although this antibacterial activity appeared to be rapidly bactericidal, it could be partly reversed by addition of deferrisiderophore , or of ferrisiderophore at high concentration, immediately after exposure of cells to the cupric-siderophore complex.
摘要
铁载体对铜的螯合作用增强了铜对巨大芽孢杆菌的毒性。尽管这种抗菌活性似乎具有快速杀菌作用，但在细胞暴露于铜 - 铁载体复合物后立即添加去铁铁载体或高浓度的铁铁载体，其抗菌活性可部分逆转。
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