Orita K, Miwa H, Yamashita H, Kurimoto M
Gan To Kagaku Ryoho. 1984 Jun;11(6):1253-6.
Antitumor effect of new lymphokine extracted from BALL-1 cells derived from human acute lymphocytic leukemia was investigated using BDF1 mice bearing Lewis lung carcinoma. This antitumor lymphokine is called OH-1. The antitumor effect of OK-1 on transplanted main tumor was great, but less effective than cyclophosphamide. However, the antitumor effect on OH-1 on metastatic tumor was comparably high as with cyclophosphamide, both macroscopically and functionally.
使用携带Lewis肺癌的BDF1小鼠，研究了从人急性淋巴细胞白血病来源的BALL-1细胞中提取的新型淋巴因子的抗肿瘤作用。这种抗肿瘤淋巴因子被称为OH-1。OK-1对移植的主肿瘤具有很大的抗肿瘤作用，但不如环磷酰胺有效。然而，OH-1对转移瘤的抗肿瘤作用在宏观和功能上与环磷酰胺相当高。
