Sheehan D V
J Clin Psychiatry. 1984 Jul;45(7 Pt 2):29-36.
Studies of the treatment of panic anxiety and various other states with monoamine oxidase (MAO) inhibitors are critically reviewed. It is concluded that MAOIs have differential effects on several dimensions of pathologic anxiety. The association between depression and anxiety states is also reviewed; it is observed that MAOIs effectively treat severe anxiety and phobic disorders without operating strictly via their antidepressant mechanism. In addition, it is proposed that biologic depression and biologic anxiety should be considered to have some independence from one another. Guidelines for the clinical delineation of anxiety disorders are provided, and the clinical and research implications of the proposal for revision of DSM-III anxiety and phobic disorders section, are outlined in detail. It is suggested that anxiety and phobic disorders be classified into endogenous (disease) and exogenous (nondisease) types.
对使用单胺氧化酶（MAO）抑制剂治疗惊恐焦虑及其他各种状态的研究进行了批判性综述。得出的结论是，单胺氧化酶抑制剂在病理性焦虑的几个维度上具有不同的作用。还对抑郁症与焦虑状态之间的关联进行了综述；观察到单胺氧化酶抑制剂可有效治疗严重焦虑和恐惧症，而并非严格通过其抗抑郁机制起作用。此外，有人提出生物性抑郁症和生物性焦虑症应被视为彼此具有一定的独立性。提供了焦虑症临床分类的指导原则，并详细概述了修订《精神疾病诊断与统计手册》第三版（DSM - III）中焦虑和恐惧症部分提议的临床及研究意义。建议将焦虑症和恐惧症分为内源性（疾病）和外源性（非疾病）类型。
