Kopple J D, Blumenkrantz M J
Kidney Int Suppl. 1983 Dec;16:S295-302.
Recent studies suggest that patients undergoing continuous ambulatory peritoneal dialysis (CAPD) may be prone to develop protein depletion. This paper reviews data concerning glucose uptake, protein and amino acid losses, and nitrogen and mineral balances in clinically stable adult CAPD patients. Approximately 70% of the glucose instilled with dialysate was absorbed, and the glucose absorbed provided approximately 8 kcal/kg/day to the patient. Serum total protein and albumin losses into dialysate averaged 8.8 +/- (SEM) 0.5 and 5.7 +/- 0.4 g/day, respectively. The quantity of free amino acids removed with dialysis was less, 3.4 +/- 0.3 g/day. The balance studies suggest that a safe dietary protein allowance for clinically stable CAPD patients who are ingesting high energy diets is 1.2 to 1.3 g/kg/day. Tentative dietary allowances for other nutrients in clinically stable CAPD patients are proposed.
近期研究表明，接受持续性非卧床腹膜透析（CAPD）的患者可能易于出现蛋白质消耗。本文回顾了有关临床稳定的成年CAPD患者葡萄糖摄取、蛋白质和氨基酸丢失以及氮和矿物质平衡的数据。注入透析液中的葡萄糖约70%被吸收，吸收的葡萄糖为患者提供约8千卡/千克/天的能量。血清总蛋白和白蛋白向透析液中的丢失平均分别为8.8±（标准误）0.5克/天和5.7±0.4克/天。透析清除的游离氨基酸量较少，为3.4±0.3克/天。平衡研究表明，对于摄入高能量饮食的临床稳定的CAPD患者，安全的饮食蛋白质摄入量为1.2至1.3克/千克/天。还提出了临床稳定的CAPD患者其他营养素的暂定饮食摄入量。
