Skurida G I, Mironov V A, Drozdov-Tikhomirov L N
Mikrobiologiia. 1984 Mar-Apr;53(2):187-94.
The paper presents a method for calculating the minimal expenses of substrates from the medium necessary to compensate energy donor disbalances in an intracellular process under study (for instance, in the production of a unit biomass or in the synthesis of one mole of monomer) between the number of regeneration events and the number of events in which each energy donor is utilized. The method employs the performance tables of energetic processes and is based on linear programming method. The paper includes the performance tables RE, RU and RS describing the stoichiometry of energetic processes in Escherichia coli, and the results of calculation for the cases of E. coli growth on glucose and acetate as sources of carbon.
本文提出了一种计算底物最小费用的方法，该费用源于为补偿所研究的细胞内过程（例如，在单位生物质生产或一摩尔单体合成中）能量供体失衡所需培养基中的底物，此失衡存在于再生事件数量与每个能量供体被利用的事件数量之间。该方法采用能量过程性能表，并基于线性规划方法。本文包含描述大肠杆菌中能量过程化学计量的性能表RE、RU和RS，以及以葡萄糖和乙酸盐作为碳源时大肠杆菌生长情况的计算结果。
