Nelson C E, Haneman W, Young K, O'Foghludha F
Med Phys. 1984 May-Jun;11(3):242-6. doi: 10.1118/1.595498.
Analytical techniques have been developed to generate electron beam isodose distributions from a modest set of experimental data. These techniques include (1) development of a compact yet powerful linear least-squares optimization program with a graphic display of the results, (2) coordinate transformations to allow straightforward fitting of the isodose distributions with simple polynomial functions, and (3) accurate interpolation methods to allow production of treatment planning dose matrices. The program, written in FORTRAN, has been implemented on a minicomputer and uses the standard peripherals of a commercially available treatment planning system (AECL TP-11). The computer-generated isodose and central-axis distributions correspond very closely with the data for electron energies from 5 to 20 MeV and for all field sizes.
已经开发出了一些分析技术，可根据一组有限的实验数据生成电子束等剂量分布。这些技术包括：（1）开发一个紧凑而强大的线性最小二乘优化程序，并对结果进行图形显示；（2）进行坐标变换，以便用简单的多项式函数直接拟合等剂量分布；（3）采用精确的插值方法，以便生成治疗计划剂量矩阵。该程序用FORTRAN编写，已在一台小型计算机上实现，并使用了市售治疗计划系统（AECL TP - 11）的标准外围设备。计算机生成的等剂量分布和中心轴分布与5至20 MeV电子能量以及所有射野大小的数据非常吻合。
