Tavori S, Tatarsky I
Am J Hematol. 1984 Jul;17(1):1-9. doi: 10.1002/ajh.2830170102.
Coagulation studies and clinical observations were carried out in 47 members belonging to three generations in one kindred. Classical Hemophilia A, Von Willebrand (VWD) variants, and normal individuals were revealed in this study. The coexistence of Hemophilia A and VWD in different siblings of the same progenitors indicates the difficulty to distinguish between these two major factor VIII abnormalities as two different traits. A hypothesis based on these findings is elaborated.
对一个家族三代中的47名成员进行了凝血研究和临床观察。本研究发现了典型的甲型血友病、血管性血友病（VWD）变异型和正常个体。同一祖先的不同兄弟姐妹中同时存在甲型血友病和VWD，这表明难以将这两种主要的凝血因子VIII异常区分为两种不同的性状。基于这些发现阐述了一个假说。
