Steele P, Kirch D, Levitt P
Am J Med. 1984 Jun 22;76(6A):58-62. doi: 10.1016/0002-9343(84)91044-1.
Ten men with coronary disease and angina-limited exercise participated in a study of the effects of sustained release nitroglycerin capsules on exercise performance and myocardial thallium images. Dose titration to ascertain the maximally tolerated dose, 6.5 to 26 mg orally four times a day, followed by double-blind, placebo-controlled cross-over treatment was undertaken. Following the administration of sustained release nitroglycerin exercise performance and exercise thallium images improved and appeared to remain so for four hours.
十名患有冠状动脉疾病且运动受心绞痛限制的男性参与了一项关于缓释硝酸甘油胶囊对运动表现和心肌铊显像影响的研究。进行剂量滴定以确定最大耐受剂量，即每日口服4次，每次6.5至26毫克，随后进行双盲、安慰剂对照的交叉治疗。服用缓释硝酸甘油后，运动表现和运动铊显像有所改善，且似乎在4小时内保持如此。
