Suarez B K, Van Eerdewegh P
Am J Med Genet. 1984 May;18(1):135-46. doi: 10.1002/ajmg.1320180117.
Two widely used affected-sib-pair scoring procedures (the Green and Woodrow [1977] procedure, and the method of forming all possible affected-sib-pairs) are compared with a new method for their relative efficiency in detecting the presence of an HLA-linked disease susceptibility gene. Their relative performance is investigated by extensive computer simulations over a large number of disease transmission models. On the average, the new procedure appears to outperform the Green and Woodrow method and the "all-possible-pairs" method.
两种广泛使用的患病同胞对评分程序（格林和伍德罗[1977]程序，以及形成所有可能的患病同胞对的方法）与一种新方法就检测HLA连锁疾病易感性基因存在的相对效率进行了比较。通过对大量疾病传播模型进行广泛的计算机模拟来研究它们的相对性能。平均而言，新程序似乎优于格林和伍德罗方法以及“所有可能对”方法。
