Franklyn J A, Sheppard M C, Ramsden D B, Hoffenberg R
Clin Endocrinol (Oxf). 1984 May;20(5):527-30. doi: 10.1111/j.1365-2265.1984.tb00100.x.
Total and free thyroid hormones were measured in a group of asymptomatic subjects with high circulating TSH concentrations and a previous history of radioiodine therapy. Subjects in the high TSH group all fell within the normal range for measurements of total T4, total T3 and T4/TBG ratio. Concentrations of free T4 or free T3 were below the normal range in more than half (9 out of 17) of the high TSH group suggesting that these measurements are more sensitive indices of thyroid failure than measurement of total hormones or T4/TBG ratio.
在一组循环促甲状腺激素（TSH）浓度高且有放射性碘治疗史的无症状受试者中测量了总甲状腺激素和游离甲状腺激素。高TSH组的受试者在总T4、总T3和T4/TBG比值的测量中均处于正常范围内。高TSH组超过一半（17例中的9例）的游离T4或游离T3浓度低于正常范围，这表明这些测量指标比总激素或T4/TBG比值测量对甲状腺功能减退更敏感。
