Shelley W B, Shelley E D
Cutis. 1984 Jun;33(6):556-7.
Two women were seen for evaluation of acrocyanosis and vasculitis limited to the toes. General studies showed only the presence of low titer cold hemagglutinins. Complete rapid clearing of the cutaneous changes was achieved after treatment with systemic cephradine in one case and penicillin in the other. This supports the view that cold agglutinins, arising as a result of occult bacterial infection, were responsible for the clinical presentation of blue toes.
两名女性因评估手足发绀症和仅局限于脚趾的血管炎前来就诊。常规检查仅发现存在低滴度冷凝集素。其中一例经全身性头孢拉定治疗，另一例经青霉素治疗后，皮肤病变均完全迅速消退。这支持了以下观点：隐匿性细菌感染产生的冷凝集素是导致蓝趾临床表现的原因。
