Corazza G R, Simeone E, Di Giammarco A M, Ciccarelli R, Tenaglia G
Minerva Med. 1978 Mar 10;69(12):758-61.
The efficacy and possible sideeffects of chenodeoxycholic acid have been studied in 35 patients with biliary calculosis lithiasis. In 53% of the cases treated for six months or more partial or complete gallstone dissolution was observed. The action of this drug on hematic triglyceride level and on severity and frequency of the hypostenic dyspeptic symptoms and biliary colic is interesting from the viewpoint of new therapeutic prospects. Diarrhea has been the only relevant side-effect.
对35例胆石症患者研究了鹅去氧胆酸的疗效及可能的副作用。在接受治疗6个月或更长时间的病例中,53%观察到部分或完全的胆结石溶解。从新的治疗前景来看,该药对血液甘油三酯水平以及对低张力消化不良症状和胆绞痛的严重程度及发作频率的作用令人关注。腹泻是唯一相关的副作用。