Chayasirisobhon S, Cullis P, Sack R, Papavasiliou A
Clin Electroencephalogr. 1984 Jul;15(3):155-8. doi: 10.1177/155005948401500307.
Two hundred nineteen grand mal discharges were reviewed in 50 epileptic patients. It was commonly seen in patients with prenatal and perinatal causes, mental deficiency with neurological deficits, and multiple types of seizures. Eighty-eight percent of the discharges were bilaterally synchronous with 49 percent of bifrontal predominance. Fifty-eight percent were associated with drowsiness or sleep, and 64 percent were associated with clinical accompaniments. The most common clinical signs were tonic movement of arms, legs or neck, eye opening, eye fluttering, head drop, etc. The increased frequency of clinical seizures usually observed during the occurrence of this pattern may provide some clues that the antiepileptic medication should be reassessed to control the oncoming seizure attacks.
对50例癫痫患者的219次癫痫大发作放电情况进行了回顾。这种情况常见于有产前和围产期病因、伴有神经功能缺损的智力缺陷以及多种类型癫痫发作的患者。88%的放电为双侧同步，其中49%以双额叶为主。58%与嗜睡或睡眠有关，64%与临床伴随症状有关。最常见的临床体征是手臂、腿部或颈部的强直性运动、睁眼、眼球颤动、头部下垂等。在这种发作模式出现期间通常观察到的临床癫痫发作频率增加，可能为重新评估抗癫痫药物以控制即将到来的癫痫发作提供一些线索。
