Harvey S, Scanes C G, Marsh J A
Gen Comp Endocrinol. 1984 Sep;55(3):493-7. doi: 10.1016/0016-6480(84)90023-6.
The basal plasma growth hormone (GH) level in adult sex-linked dwarf hens was elevated in comparison with autosomal dwarf hens and with control (Cornell K strain) laying hens. The iv administration of thyrotrophin-releasing hormone (TRH) (10 micrograms/kg) had no effect on GH secretion in control hens but slightly (1.2-fold) and transiently (for 10 min) increased the GH level in the autosomal dwarfs and greatly (8.7-fold) increased the GH level in the sex-linked dwarfs, in which it remained elevated for at least 30 min after injection. The iv administration of human pancreatic GH-releasing factor (hpGRF) (10 micrograms/kg) stimulated GH release in each strain. The response in the sex-linked dwarfs was greater than that in the autosomal dwarfs and the control hens but less than that elicited by TRH. These results suggest that the increased basal GH level in the sex-linked dwarfs results from an increased responsiveness to provocative stimulation.
与常染色体矮小母鸡和对照（康奈尔K系）产蛋母鸡相比，成年性连锁矮小母鸡的基础血浆生长激素（GH）水平升高。静脉注射促甲状腺激素释放激素（TRH）（10微克/千克）对对照母鸡的GH分泌无影响，但使常染色体矮小母鸡的GH水平略有（1.2倍）且短暂（10分钟）升高，并使性连锁矮小母鸡的GH水平大幅（8.7倍）升高，注射后至少30分钟内该水平一直保持升高。静脉注射人胰腺生长激素释放因子（hpGRF）（10微克/千克）刺激了每个品系的GH释放。性连锁矮小母鸡的反应大于常染色体矮小母鸡和对照母鸡，但小于TRH引起的反应。这些结果表明，性连锁矮小母鸡基础GH水平的升高是由于对刺激性刺激的反应性增加所致。
