文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Ahene C A, Lea R W, Harvey S

Department of Physiology, University of Alberta, Edmonton Canada.

Comp Biochem Physiol A Comp Physiol. 1991;98(1):103-6. doi: 10.1016/0300-9629(91)90585-z.

Basal circulating growth hormone (GH) concentrations in sex-linked-dwarf (SLD) chickens were unaffected by the intracerebroventricular (icv) injection of 10, 50 or 100 micrograms somatostatin (SRIF). 2. The GH response to systemic thyrotropin-releasing hormone (TRH; 10 micrograms/kg, iv) was, however, 'paradoxically' enhanced 20 min after icv SRIF administration. 3. A lower dose (1.0 micrograms) of SRIF had no effect on basal or TRH-induced GH release. 4. High-titre SRIF antisera (4 microliters) also had no acute effect on basal plasma GH concentrations, but augmented the GH response to TRH challenge. 5. SRIF would appear to act at central sites to modulate stimulated GH secretion in SLD chickens.

性连锁矮小（SLD）鸡的基础循环生长激素（GH）浓度不受脑室内（icv）注射10、50或100微克生长抑素（SRIF）的影响。2. 然而，在icv给予SRIF 20分钟后，对全身促甲状腺激素释放激素（TRH；10微克/千克，静脉注射）的GH反应“反常地”增强。3. 较低剂量（1.0微克）的SRIF对基础或TRH诱导的GH释放没有影响。4. 高滴度SRIF抗血清（4微升）对基础血浆GH浓度也没有急性影响，但增强了对TRH刺激的GH反应。5. SRIF似乎在中枢部位起作用，以调节SLD鸡中受刺激的GH分泌。

Ahene C A, Lea R W, Harvey S

Department of Physiology, University of Alberta, Edmonton Canada.

Comp Biochem Physiol A Comp Physiol. 1991;98(1):103-6. doi: 10.1016/0300-9629(91)90585-z.

Basal circulating growth hormone (GH) concentrations in sex-linked-dwarf (SLD) chickens were unaffected by the intracerebroventricular (icv) injection of 10, 50 or 100 micrograms somatostatin (SRIF). 2. The GH response to systemic thyrotropin-releasing hormone (TRH; 10 micrograms/kg, iv) was, however, 'paradoxically' enhanced 20 min after icv SRIF administration. 3. A lower dose (1.0 micrograms) of SRIF had no effect on basal or TRH-induced GH release. 4. High-titre SRIF antisera (4 microliters) also had no acute effect on basal plasma GH concentrations, but augmented the GH response to TRH challenge. 5. SRIF would appear to act at central sites to modulate stimulated GH secretion in SLD chickens.

性连锁矮小（SLD）鸡的基础循环生长激素（GH）浓度不受脑室内（icv）注射10、50或100微克生长抑素（SRIF）的影响。2. 然而，在icv给予SRIF 20分钟后，对全身促甲状腺激素释放激素（TRH；10微克/千克，静脉注射）的GH反应“反常地”增强。3. 较低剂量（1.0微克）的SRIF对基础或TRH诱导的GH释放没有影响。4. 高滴度SRIF抗血清（4微升）对基础血浆GH浓度也没有急性影响，但增强了对TRH刺激的GH反应。5. SRIF似乎在中枢部位起作用，以调节SLD鸡中受刺激的GH分泌。