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阿洛西林纸片药敏试验的解释标准及暂定质量控制限度

Interpretive criteria and tentative quality control limits for apalcillin disk susceptibility tests.

作者信息

Barry A L, Thornsberry C, Jones R N, Gavan T L

出版信息

J Clin Microbiol. 1984 Jun;19(6):777-82. doi: 10.1128/jcm.19.6.777-782.1984.

Abstract

In vitro studies with 661 bacterial isolates were performed to establish interpretive criteria. In addition, a nine-laboratory study was performed to establish quality control limits for tests with 100-micrograms apalcillin disks and to confirm testing criteria for tests with 100-micrograms piperacillin disks. The two drugs were very similar, and nearly identical criteria were recommended for interpretation and for control of the two types of disks. Neither disk is recommended for testing Staphylococcus spp. or Haemophilus spp.; with other microorganisms, zone size limits of less than or equal to 13 mm (resistant) and greater than or equal to 18 mm (susceptible) are proposed for tests with 100-micrograms apalcillin disks.

摘要

对661株细菌分离株进行了体外研究以建立解释标准。此外,开展了一项由九个实验室参与的研究,以确定使用100微克阿帕西林纸片进行检测的质量控制限度,并确认使用100微克哌拉西林纸片进行检测的标准。这两种药物非常相似,因此建议对这两种类型的纸片采用几乎相同的解释和控制标准。不建议使用任何一种纸片检测葡萄球菌属或嗜血杆菌属;对于其他微生物,建议使用100微克阿帕西林纸片检测时,抑菌圈直径小于或等于13毫米(耐药)和大于或等于18毫米(敏感)。

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