碘海醇的人体药理学试验。
Human pharmacologic trials with iohexol.
作者信息
Aakhus T, Dahlström K, Shaw D D, Leese P T, March L
出版信息
Acta Radiol Suppl. 1983;366:20-2.
PMID:6433655
Abstract
Injections of iohexol in two series of volunteers, 20 in 1980 and 16 in 1982 are briefly reported. Intravenous injections of iohexol in doses from 125 to 1500 mg I/kg body weight were well tolerated. Iohexol was completely excreted in unchanged form. The results indicate that iohexol may safely be used in clinical trials.
摘要
简要报告了两组志愿者注射碘海醇的情况，1980年有20名志愿者，1982年有16名志愿者。静脉注射碘海醇的剂量为125至1500毫克碘/千克体重，耐受性良好。碘海醇以原形完全排出。结果表明，碘海醇可安全用于临床试验。
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