Katoh T, Bosslet K, Kurrle R, Sedlacek H H, Seiler F R
Behring Inst Mitt. 1984 May(74):49-54.
The specificity of two murine monoclonal antibodies (BW 252/104, IgG3 and BW 241/10, IgM) which recognize two different antigens is described. BW 252/104 recognizes an epitope detectable on all human cell lines and most of the human tissues tested. On account of this reactivity this antibody could be said to possess a "pan human" specificity. BW 241/10 is mainly reactive with human granulocytes but shows some binding to certain solid tissues (breast, stomach). Because of its lack of reactivity to human lymphocytes and monocytes this antibody could be of interest in the detection of human granulocytes.
描述了两种识别不同抗原的鼠单克隆抗体（BW 252/104，IgG3和BW 241/10，IgM）的特异性。BW 252/104识别在所有测试的人类细胞系和大多数人类组织上都可检测到的一个表位。由于这种反应性，该抗体可被认为具有“泛人类”特异性。BW 241/10主要与人粒细胞反应，但也显示出与某些实体组织（乳腺、胃）有一定结合。由于其对人淋巴细胞和单核细胞缺乏反应性，该抗体在人粒细胞检测中可能会有应用价值。
