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使用超活性促黄体生成激素释放激素(LHRH)激动剂治疗月经过多。

Use of a superactive luteinizing hormone releasing hormone (LHRH) agonist in the treatment of menorrhagia.

作者信息

Shaw R W, Fraser H M

出版信息

Br J Obstet Gynaecol. 1984 Sep;91(9):913-6. doi: 10.1111/j.1471-0528.1984.tb03708.x.

DOI:10.1111/j.1471-0528.1984.tb03708.x
PMID:6433966
Abstract

A luteinizing hormone releasing hormone agonist, D-Ser(But)6des Gly10-LHRH ethylamide, was administered intranasally to four women with unexplained ovulatory menorrhagia. Dramatic reductions in excessive menstrual blood losses were induced without significant side-effects, although the pattern of loss returned to pretreatment levels within 2 months of ceasing therapy.

摘要

向四名不明原因排卵性月经过多的女性鼻内给药一种促黄体生成素释放激素激动剂,即D-丝氨酸(叔丁基)6 -去甘氨酸10 -促黄体生成素释放激素乙酰胺。尽管在停止治疗后2个月内失血模式恢复到治疗前水平,但过度月经失血显著减少,且无明显副作用。

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Use of a superactive luteinizing hormone releasing hormone (LHRH) agonist in the treatment of menorrhagia.使用超活性促黄体生成激素释放激素(LHRH)激动剂治疗月经过多。
Br J Obstet Gynaecol. 1984 Sep;91(9):913-6. doi: 10.1111/j.1471-0528.1984.tb03708.x.
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Fertil Steril. 1981 Sep;36(3):339-42. doi: 10.1016/s0015-0282(16)45735-3.
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Long-term intranasal luteinizing hormone-releasing hormone agonist treatment for contraception in women.
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Luteinizing hormone releasing hormone agonist for contraception in breast feeding women.用于哺乳期妇女避孕的促黄体生成素释放激素激动剂。
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Inhibition of ovulation during discontinuous intranasal luteinizing hormone-releasing hormone agonist dosing in combination with gestagen-induced bleeding.在间断经鼻给予促黄体生成素释放激素激动剂并联合孕激素诱导出血期间对排卵的抑制作用。
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Chronic treatment with the gonadotropin-releasing hormone agonist D-Ser(TBU)6-EA10-LRH for contraception in women and men.使用促性腺激素释放激素激动剂D-Ser(TBU)6-EA10-LRH对女性和男性进行长期避孕治疗。
Int J Fertil. 1980;25(3):239-46.
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Reversible hypogonadism induced by a luteinizing hormone-releasing hormone (LH-RH) agonist (Buserelin) as a new therapeutic approach for endometriosis.促黄体生成素释放激素(LH-RH)激动剂(布舍瑞林)诱导的可逆性性腺功能减退作为子宫内膜异位症的一种新治疗方法。
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Effect of LHRH agonist (buserelin) on pulsatile secretion of LHRH and LH.
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Fourteen-day versus twenty-one-day regimens of intermittent intranasal luteinizing hormone-releasing hormone agonist combined with an oral progestogen as antiovulatory contraceptive approach.间歇性鼻内注射促黄体生成素释放激素激动剂联合口服孕激素作为抗排卵避孕方法的14天与21天方案
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Intranasal treatment with luteinising hormone releasing hormone agonist in women with endometriosis.在患有子宫内膜异位症的女性中使用促黄体生成素释放激素激动剂进行鼻内治疗。
Br Med J (Clin Res Ed). 1983 Dec 3;287(6406):1667-9. doi: 10.1136/bmj.287.6406.1667.

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GnRH agonists and antagonists. Current clinical status.促性腺激素释放激素激动剂和拮抗剂。当前临床状况。
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Risk-benefit assessment of drugs used for the treatment of menstrual disorders.
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Menorrhagia. Current drug treatment concepts.
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