Altavilla D, Matera G, Padovano I, Saija A, Mondello F, Miragliotta G, Foca' A
G Batteriol Virol Immunol. 1983 Jan-Jun;76(1-6):43-7.
Administration of E. coli LPS prior to 3.5 mg/Kg dose of thiourea has been reported to protect rats against pulmonary edema and pleural effusion. However, LPS of Shigella sonnei (either in phase I or II) did not show any protective effect. These data might suggest a different mechanism of endotoxins on membranes.
据报道,在给予3.5毫克/千克剂量的硫脲之前给予大肠杆菌脂多糖可保护大鼠免受肺水肿和胸腔积液的影响。然而,宋内志贺氏菌的脂多糖(I期或II期)未显示出任何保护作用。这些数据可能表明内毒素对细胞膜的作用机制不同。