Kristerson L, Andreasen J O
Int J Oral Surg. 1984 Aug;13(4):324-33. doi: 10.1016/s0300-9785(84)80040-x.
The effect of damage to the follicle and of superficial positioning of tooth germs after replantation or autotransplantation was studied in green Vervet monkeys. Radiographs were taken immediately after surgery and 3, 6 and 9 months postoperatively, whereafter the animals were sacrificed. The tissue blocks were sectioned in step serial sections along a frontal plane and histologic and radiographic evaluation was made. Tooth germs whose follicle was either damaged or removed showed no sign of eruption, while tooth germs which were replanted with an intact follicle were fully erupted within 3 months. Non-operated control teeth were fully erupted within 6 months. Histologic examination revealed that roots of replanted teeth were only slightly shorter than the non-operated control teeth. Transplantation of tooth germs in different positions in relation to the alveolar crest showed that teeth placed in their original position attained an average tooth length of 12.5 mm, whereas teeth placed in a semi-erupted position achieved an average length of only 9.7 mm. A control group of non-operated incisors demonstrated an average tooth length of 13.7 mm. This study indicates that damage to the follicle at the time of replantation of tooth germs is of major importance for tooth eruption and that placing tooth germs in a semi-erupted position adversely influences later root development.
在绿长尾猴身上研究了牙胚再植或自体移植后毛囊损伤及牙胚浅表定位的影响。术后立即及术后3、6和9个月拍摄X光片，之后处死动物。将组织块沿额面制成连续切片，进行组织学和放射学评估。毛囊受损或被移除的牙胚没有萌出迹象，而带着完整毛囊再植的牙胚在3个月内完全萌出。未手术的对照牙在6个月内完全萌出。组织学检查显示，再植牙的牙根仅比未手术的对照牙略短。将牙胚移植到相对于牙槽嵴的不同位置表明，置于原位置的牙齿平均牙长为12.5毫米，而置于半萌出位置的牙齿平均长度仅为9.7毫米。一组未手术的对照切牙平均牙长为13.7毫米。本研究表明，牙胚再植时毛囊损伤对牙齿萌出至关重要，且将牙胚置于半萌出位置会对后期牙根发育产生不利影响。
