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口腔黏膜鳞状细胞癌:澳大利亚244例病例回顾

Squamous cell carcinoma of the oral mucosa: a review of 244 cases in Australia.

作者信息

Rich A M, Radden B G

出版信息

J Oral Pathol. 1984 Oct;13(5):459-71. doi: 10.1111/j.1600-0714.1984.tb01447.x.

DOI:10.1111/j.1600-0714.1984.tb01447.x
PMID:6434714
Abstract

In an attempt to extend and update information relating to oral cancer in Australia and to provide a basis for international comparison a group of 244 patients suffering from oral cancer have been studied in detail. These patients were all diagnosed in one Oral Pathology Biopsy Service used almost exclusively by oral surgeons and dentists, and although this introduced bias into the sample it had the advantage of standardising documentation. The male: female ratio (1.3 : 1) of patients with oral cancer was lower than that previously reported in Australia, but the average age of patients (60 years) was comparable with many previous reports. The floor of the mouth was the most common site of cancer. There was a significant over-representation of tobacco and alcohol consumers amongst the patients, but a group of elderly females who had never used tobacco or alcohol, yet developed oral cancer, was identified. It was of particular interest that these elderly females had significantly lower haemoglobin and serum iron levels than a sex- and age-matched control group.

摘要

为了扩充和更新澳大利亚口腔癌的相关信息,并提供国际比较的基础,对一组244例口腔癌患者进行了详细研究。这些患者均在一个几乎仅由口腔外科医生和牙医使用的口腔病理活检服务机构被诊断,尽管这给样本带来了偏差,但它具有使文档标准化的优势。口腔癌患者的男女比例(1.3:1)低于澳大利亚此前报告的比例,但患者的平均年龄(60岁)与许多此前的报告相当。口腔底部是最常见的癌症部位。患者中烟草和酒精消费者的比例显著过高,但也发现了一组从未使用过烟草或酒精却患口腔癌的老年女性。特别有趣的是,这些老年女性的血红蛋白和血清铁水平明显低于性别和年龄匹配的对照组。

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引用本文的文献

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Relationship between Menopausal Hormone Therapy and Oral Cancer: A Cohort Study Based on the Health Insurance Database in South Korea.更年期激素治疗与口腔癌的关系:一项基于韩国健康保险数据库的队列研究。
J Clin Med. 2022 Oct 2;11(19):5848. doi: 10.3390/jcm11195848.
2
Assessment of proliferating cell nuclear antigen (PCNA) expression at the invading front of oral squamous cell carcinoma.评估口腔鳞状细胞癌侵袭前沿的增殖细胞核抗原(PCNA)表达。
BMC Oral Health. 2019 Oct 31;19(1):233. doi: 10.1186/s12903-019-0928-9.
3
Gender-related hormonal risk factors for oral cancer.
口腔癌的性别相关激素风险因素。
Pathol Oncol Res. 2007;13(3):195-202. doi: 10.1007/BF02893499. Epub 2007 Oct 7.
4
Suprabasal 40 kd keratin (K19) expression as an immunohistologic marker of premalignancy in oral epithelium.基底上层40kd角蛋白(K19)表达作为口腔上皮癌前病变的免疫组织学标志物。
Am J Pathol. 1989 Jan;134(1):89-98.