Gralewski Z
Neurol Neurochir Pol. 1984 Mar-Apr;18(2):131-5.
Using ultrasonographic measurements based on Doppler's phenomenon the author determined in 86 subjects the velocity of blood flow in the common carotid arteries before and after breathing 6% CO2. Acceleration of blood flow resulting from dilation of cerebral blood vessels was observed in all healthy subjects up to the age of 45 years. In older subjects the vasomotor reaction was sometimes absent, significantly more frequently in cases of past cerebrovascular accidents. These results indicate absence of vasomotor reserve in most patients with disturbances of cerebral circulation. The used method of investigation makes possible, in view of its simplicity and non-invasiveness, a more widespread determination of cerebral vascular reactions in clinical studies.
作者采用基于多普勒现象的超声测量方法,测定了86名受试者在呼吸6%二氧化碳前后颈总动脉中的血流速度。在所有45岁以下的健康受试者中,均观察到由于脑血管扩张导致的血流加速。在老年受试者中,血管舒缩反应有时缺失,在既往有脑血管意外的病例中更为常见。这些结果表明,大多数脑循环障碍患者缺乏血管舒缩储备。鉴于其简单性和非侵入性,所采用的研究方法使得在临床研究中更广泛地测定脑血管反应成为可能。