Harzbecker K
Z Erkr Atmungsorgane. 1984;163(1):6-13.
The following study was undertaken as a contribution to a therapeutic programme of pulmonary hypertension. The existence of a functional vascular component in patients suffering from silicosis complicated by chronic latent or manifest pulmonary hypertension has to be assumed. In these cases a therapeutic influence of aminophylline could be observed. The influence of repeated exercise was discerned by means of control group. Furthermore the importance of a rapid analysis of drug serum concentration during investigation by means of high pressure liquid chromatography could be demonstrated.
以下研究是作为对肺动脉高压治疗方案的一项贡献而开展的。必须假定患有矽肺并伴有慢性潜在或明显肺动脉高压的患者存在功能性血管成分。在这些病例中,可以观察到氨茶碱的治疗作用。通过对照组可以看出重复运动的影响。此外,通过高压液相色谱法在研究过程中快速分析药物血清浓度的重要性也得到了证明。