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[人血清对凝集素激活的人淋巴细胞中氚标记胸腺嘧啶核苷掺入的刺激作用:生长激素依赖性及其局限性的证明]

[Stimulating action of human serum on the incorporation of tritiated thymidine in human lymphocytes activated by lectins: demonstration of the GH-dependency and its limitations].

作者信息

Schimpff R M, Bozzola M

出版信息

C R Acad Sci III. 1984;299(7):235-7.

PMID:6435820
Abstract

Using thymidine uptake by activated human lymphocytes to measure the growth-stimulating activity of human serum, the authors demonstrate that thymidine activity was significantly correlated (p less than 0.001) with GH levels. r = 0.729 when GH values are below 3.5 ng/ml, r = 0.509 when GH values are below 8 ng/ml and r = 0.337 for all of the patients. Low levels of GH are sufficient for the generation of this activity.

摘要

作者利用活化的人淋巴细胞对胸苷的摄取来测量人血清的生长刺激活性,结果表明胸苷活性与生长激素(GH)水平显著相关(p<0.001)。当GH值低于3.5 ng/ml时,r = 0.729;当GH值低于8 ng/ml时,r = 0.509;对所有患者而言,r = 0.337。低水平的GH足以产生这种活性。

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