Scott R, Ferrie B, McLelland A, Fell G S
Urol Res. 1984;12(4):213-5. doi: 10.1007/BF00256806.
The effect of 96 mg methylprednisolone on trace metals and hormone levels was measured in 13 males with sub-fertility associated with an antibody problem. Over a period of 5 days the serum zinc was significantly reduced (p less than 0.05) as was the serum testosterone (p less than 0.01). By contrast the luteinising hormone levels rose (p less than 0.01) within 3 days of administration of the steroid. The lability of serum zinc to the administration of steroids is further demonstrated by its significant fall (p less than 0.01) after 3 days of therapy. These results suggest an adreno-cortical control of zinc in serum.
在13名因抗体问题导致生育力低下的男性中，测定了96毫克甲基强的松龙对微量元素和激素水平的影响。在5天的时间里，血清锌显著降低（p小于0.05），血清睾酮也显著降低（p小于0.01）。相比之下，在给予类固醇后的3天内，促黄体生成素水平升高（p小于0.01）。治疗3天后血清锌的显著下降（p小于0.01）进一步证明了血清锌对类固醇给药的不稳定反应。这些结果表明肾上腺皮质对血清锌有调控作用。
