Pichard C, Roulet M
Clin Otolaryngol Allied Sci. 1984 Aug;9(4):209-14. doi: 10.1111/j.1365-2273.1984.tb01499.x.
The incidence of protein and calorie malnutrition in bucco-pharyngeal cancer patients is high and therefore nutritional support is indicated. Two methods of tube feeding, fractioned enteral (FEN) versus constant rate enteral nutrition (CREN) have been compared in a prospective study. Based on anthropometrical, biological and immunological criteria, patients on CREN showed a significant improvement of their post-operative protein state in comparison with patients on FEN. This difference was due to a better tolerance to CREN, which allowed a more appropriate protein and calorie intake. Furthermore the time of intravenous infusion was reduced in patients on CREN. In conclusion, CREN is a highly efficient feeding method for patients with head and neck cancer. It has the great advantage of being simple and cheap.
口腔咽癌患者中蛋白质和热量营养不良的发生率很高,因此需要进行营养支持。在一项前瞻性研究中,对两种管饲方法进行了比较,即分次肠内营养(FEN)与恒速肠内营养(CREN)。根据人体测量、生物学和免疫学标准,与接受FEN的患者相比,接受CREN的患者术后蛋白质状态有显著改善。这种差异是由于对CREN的耐受性更好,从而能够摄入更合适的蛋白质和热量。此外,接受CREN的患者静脉输注时间缩短。总之,CREN是头颈部癌患者一种高效的喂养方法。它具有简单且成本低的巨大优势。