Bourzai M, Malauzat C, Lagorce J, Babin A
Poumon Coeur. 1978;34(1):71-6.
The authors present a case of abusive use of nitrogen in aerosol. It produced an acute edema primarily toxic bringing a hypoxemia amidst the coronarian network already partially occluded. It is rapidly followed by a subendocardiac infarct of the myocardium with left ventricular failure. The abnormal gas exchanges (alveolo-capillary block) taking place on the 15th day are discussed. Autopsy revealed a typical "cardiac lung", the presence of hyalin membranes and an early fibroblastic proliferation. These abnormalities corroborate the hemodynamic character, perhaps toxic, of pulmonary lesions.
作者报告了一例气雾剂中氮气滥用的病例。它引发了主要为中毒性的急性水肿,在已部分阻塞的冠状动脉网络中导致低氧血症。随后迅速出现心肌心内膜下梗死并伴有左心室衰竭。文中讨论了第15天发生的异常气体交换(肺泡-毛细血管阻滞)。尸检显示典型的“心源性肺”、透明膜的存在以及早期成纤维细胞增殖。这些异常证实了肺部病变的血流动力学特征,可能具有毒性。