Möller A, Ackermann R, Thun F
Fortschr Neurol Psychiatr. 1984 Oct;52(10):358-61. doi: 10.1055/s-2007-1002205.
Migraine accompagnée is associated with cerebral signs of irritation or failure, aphasic or paraphasic disturbances and Jacksonian attacks which appear together with the migraine attack. Present-day ideas on the pathogenesis of migraine headache indicate that such cerebral focal signs should be ascribed to vessel-dependent changes with transitory ischaemia. The article reports on a 24-year-old woman patient who had three Jacksonian attacks within a severe attack of migraine besides neurological signs originating from various cerebrovascular areas, as well as certain mental anomalies; this patient had a previous history of migraine with familial affiliations. The computerized tomogram, produced on the 5th day of disease, showed frontally-paramedially a zone with unsharp outlines without enhancement after administration of a contrast medium. All neurological signs, including the Jacksonian attacks, gradually receded in the course of time. Extensive additional diagnosis was performed, including angiography, to exclude any other underlying disease which could have been made responsible for the observed symptoms.
偏头痛伴发症与脑刺激或功能衰竭的体征、失语或言语错乱障碍以及与偏头痛发作同时出现的杰克逊癫痫发作有关。当今关于偏头痛性头痛发病机制的观点表明,此类脑局灶性体征应归因于与短暂性缺血相关的血管依赖性变化。本文报道了一名24岁女性患者,在一次严重的偏头痛发作期间出现了三次杰克逊癫痫发作,此外还有源自不同脑血管区域的神经体征以及某些精神异常;该患者既往有偏头痛病史且有家族遗传倾向。在疾病第5天进行的计算机断层扫描显示,在前内侧有一个边界模糊的区域,注射造影剂后无强化。随着时间的推移,所有神经体征,包括杰克逊癫痫发作,都逐渐消退。进行了广泛的额外诊断,包括血管造影,以排除任何可能导致所观察到症状的其他潜在疾病。