通过在乙烯马来酸酐聚电解质上进行分级分离从VIII因子浓缩物中去除乙肝病毒。
The removal of hepatitis B virus from factor VIII concentrates by fractionation on ethylene maleic anhydride polyelectrolyte.
作者信息
Galpin S A, Karayiannis P, Middleton S M, Thomas H C
出版信息
J Med Virol. 1984;14(3):229-33. doi: 10.1002/jmv.1890140306.
PMID:6438276
Abstract
Chromatography with a solid-phase polyelectrolyte based on ethylene maleic anhydride polyelectrolyte (EMA PE) has been shown to remove a large proportion of hepatitis B surface antigen (HBsAg), including hepatitis B virus (HBV) particles, from contaminated cryoprecipitate. This process may reduce the risk of transmission of HBV infection when factor VIII concentrates are administered.
摘要
基于乙烯马来酸酐聚电解质（EMA PE）的固相聚电解质色谱法已被证明能从受污染的冷沉淀中去除大部分乙肝表面抗原（HBsAg），包括乙肝病毒（HBV）颗粒。当输注凝血因子VIII浓缩物时，这一过程可能会降低HBV感染传播的风险。
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