Branchevskii L L
Probl Endokrinol (Mosk). 1978 Mar-Apr;24(2):98-102.
It was shown in experiments on dogs that intravenous injection of adrenaline or noradrenaline in a dose of 2 microgram/kg per min was accompanied by an increase of resistance of the renal vessels with unchanged general renal circulation, and administration of adrenaline against the background of obsidan action--by an increase of resistance and reduction of blood flow, and--against the background of phentholamine action--by a reduction of resistance with unchanged circulation. On the basis of these data and those obtained by the author earlier a supposition is put forward on a possible mechanism of a combination of functions in the systems of circulation and excrection in the control of general water-salt homeostatis in extraordinary hemodynamic shifts with the participation of the humoral factor--renin-angiotensine system.
在对狗的实验中发现,以每分钟2微克/千克的剂量静脉注射肾上腺素或去甲肾上腺素时,肾血管阻力增加,而肾脏总体循环不变;在奥昔旦作用的背景下给予肾上腺素,会导致阻力增加和血流量减少;在酚妥拉明作用的背景下给予肾上腺素,则会使阻力降低而循环不变。基于这些数据以及作者先前获得的数据,提出了一种关于在体液因素——肾素-血管紧张素系统参与下,在异常血流动力学变化中控制总体水盐稳态时循环系统和排泄系统功能联合作用的可能机制的假设。