抗肿瘤药物组合在玻璃体切割术灌注液中的毒性
Toxicity of antineoplastic drug combinations in vitrectomy infusion fluid.
作者信息
Peyman G A, Barrada A, Greenberg D, Stelmack T, Fiscells R, Yue B
出版信息
Ophthalmic Surg. 1984 Oct;15(10):844-6.
PMID:6438571
Abstract
We evaluated a combination of various antineoplastic drugs used in vitrectomy infusion fluid for toxicity. A combination of 250 micrograms/ml of 5-fluorouracil with each of the following agents, 8.0 micrograms/ml of thiotepa or 40 micrograms/ml of etoposide, or 0.1 micrograms/ml doxorubicin, or 0.1 microgram/ml vincristine was tolerated well in the rabbit eyes.
摘要
我们评估了用于玻璃体切割术灌注液中的多种抗肿瘤药物组合的毒性。250微克/毫升的5-氟尿嘧啶与以下每种药物联合使用时，即8.0微克/毫升的噻替派或40微克/毫升的依托泊苷，或0.1微克/毫升的阿霉素，或0.1微克/毫升的长春新碱，在兔眼中耐受性良好。
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