Aymard J P, Janot C, Briquel M E, Perrier P, Gaillard S, Alexandre P, Streiff F
Rev Fr Transfus Immunohematol. 1984 Sep;27(4):473-7. doi: 10.1016/s0338-4535(84)80144-0.
We have studied a group of 31 hemophiliac patients (hemophilia A: 26 patients, hemophilia B: 5 patients); 29 healthy men were used as controls. Hemophiliac patients had increased percentages of suppressor T-lymphocytes and depressed T4/T8 ratios. These abnormalities were found to be significantly correlated with the amount of F VIII used per year.
我们研究了一组31名血友病患者(甲型血友病:26例,乙型血友病:5例);29名健康男性作为对照。血友病患者抑制性T淋巴细胞百分比增加,T4/T8比值降低。发现这些异常与每年使用的F VIII量显著相关。