Susceptibility of volume stress in Colisa fasciatus.

Intraperitoneal injections of 0.6% NaC1, commonly used as injection vehicle, at 10 mul/g, but not at 5 mul/g. elicit significant (p less than .05) transitory erythropenia, leucopenia, and thrombopenia at selected post-injection time intervals in female Colisa fasciatus, a fresh water teleost. It is suggested that administration of large volumes of injection fluid per gram body weight of experimental animals should be avoided lest it might distort physiological parameters, particularly those relating to blood components, under study.