Oie B K, Hertel J, Seip M, Friis-Hansen B
Scand J Haematol. 1984 Nov;33(5):466-70. doi: 10.1111/j.1600-0609.1984.tb00726.x.
A young woman with acquired chronic pure red cell aplasia (PRCA) gave birth to 3 infants with foetal hydrops. The 1st infant died shortly after birth, while the 2nd was stillborn with severe anaemia. Both had signs of increased erythropoiesis at autopsy. The 3rd infant was saved by foetal intrauterine red cell transfusions into the hepatic part of the umbilical vein. This infant had red cell aplasia lasting for about 3 months after birth, but then recovered. We believe that antibodies to red cell progenitors in the bone marrow were transferred transplacentally from mother to foetus, giving rise to severe affection of these infants. To the best of our knowledge this has not been reported previously in PRCA.
一名患有获得性慢性纯红细胞再生障碍性贫血（PRCA）的年轻女性产下了3名患有胎儿水肿的婴儿。第一名婴儿出生后不久死亡，第二名婴儿则因严重贫血而死产。两人尸检时均有红细胞生成增加的迹象。第三名婴儿通过向脐静脉肝部进行胎儿宫内红细胞输血得以挽救。这名婴儿出生后红细胞再生障碍持续了约3个月，但随后康复。我们认为，骨髓中红细胞祖细胞的抗体通过胎盘从母亲转移至胎儿，导致这些婴儿受到严重影响。据我们所知，此前PRCA中尚未有过此类报道。
